Cheap Flights From Chicago To South America

Select sites to compare prices |
  • Select all
  • Deselect all

Find Flights


Enter your destination to continue
Enter depart date to continue
Enter return date to continue
Select at least 3 sites to continue
Select your depart date
Select your return date
Location services timed out
Enable Location Services Required!
Location services not available at this time
Use current location

Cheap flights from Chicago (CHI) to popular destinations in South America

Carrier Departure Date Return Date Lowest Price
Copa Apr 15, 2020 Apr 21, 2020 $283
JetBlue Feb 3, 2020 Feb 10, 2020 $295
JetBlue Feb 3, 2020 Feb 12, 2020 $295
Spirit Nov 5, 2019 Nov 12, 2019 $317
Spirit Sep 24, 2019 Oct 1, 2019 $326
Spirit Oct 8, 2019 Oct 15, 2019 $327
Spirit Oct 22, 2019 Oct 29, 2019 $327
Spirit Oct 29, 2019 Nov 5, 2019 $327
Copa Apr 7, 2020 Apr 14, 2020 $332
Copa Sep 19, 2019 Sep 26, 2019 $333

Cheap Last Minute Flights from Chicago to South America

Looking for cheap last minute flights or a weekend getaway? We've got you covered with weekend flight deals from Chicago to South America. The chart below shows the best last minute deals and cheap flights this weekend we could find.

Armenia 9/5/19 9/8/19 $491
Cali 9/12/19 9/16/19 $407
Medellin 9/12/19 9/16/19 $479
Bogota 9/13/19 9/16/19 $434
Cartagena 9/19/19 9/22/19 $336

Flight Schedule Summaries Last modified: Aug 20, 2019 3:42 -04:00Number of routes searched: 1,157Number of itineraries searched: 1,989,937

Chicago to Sao Paulo
Airline Connections Mon Tue Wed Thu Fri Sat Sun
Azul -
United -
American DFW
American JFK
American LAX
American MCO
American MIA
Air Canada YUL
Air Canada YYZ
Air France CDG
AeroMexico MEX
Alitalia FCO
British Airways LHR
Copa PTY
Major Airlines ATL
Major Airlines JFK
Iberia BCN
Iberia MAD
Lufthansa FRA
Lufthansa MUC
Swiss ZRH
Turkish IST
Tap Portugal LIS
United EWR
United IAD
United IAH
United FLL

We are updating our Cookie Policy. FareCompare will use cookies and other tracking technologies to assist with navigation and product selection, analyze your use of our services, assist with our promotional and marketing efforts, and provide deals content from third parties.

Cheap Flights from Chicago to South America, from $283 Round trip from CHI to South America