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Cheap Flights from Des Moines to San Francisco - DSM to SFO

Did You Know?

Delta Air Lines has 490 connecting flights between Des Moines, IA and San Francisco.
You must make at least one connection to fly from Des Moines, IA to San Francisco.

Cheap Domestic Flights from Des Moines - DSM

Flights
Airline
Lowest Price
US Airways, American, Delta
$324
US Airways, Delta, United, American
$333
US Airways, Delta, United, American
$344
Alaska, United, Delta, US Airways, Frontier, American
$273
Frontier, US Airways, American, United, Delta
$242

Cheap Domestic Flights to San Francisco - SFO

Flights
Airline
Lowest Price
Alaska, American, AirTran, Frontier, US Airways, Delta, United
$273
United, Alaska, Delta, American, US Airways, Frontier
$211
Alaska, American, US Airways, Frontier, Delta, United
$273
US Airways, United, Delta, American
$433
Alaska, Delta, US Airways, United
$485
Delta, American
$349
Alaska, US Airways, Delta, American, AirTran
$321
Alaska, Delta, US Airways
$333
Delta, American
$385
US Airways, Alaska, United, American, Delta
$321
Delta, US Airways, United, American, Alaska
$333
US Airways, Delta, American, United, Alaska
$341
United, Delta, US Airways, American
$309
American, Alaska, United, Delta, US Airways
$387
American, US Airways, United, Alaska, Frontier, Delta
$211
United, American, Delta, US Airways
$309
AirTran, Frontier, US Airways, Delta, United, Alaska, American
$99
AirTran, Frontier, American, US Airways, Delta, United, Alaska
$182
Frontier, American, US Airways, Delta, United, Alaska
$211
American, US Airways, United, Delta
$309
United, American, US Airways
$357
American, US Airways, Delta, United
$309
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Cheap Flights from Des Moines to San Francisco, from $273 Round trip from DSM to SFO