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Cheap Flights from Des Moines to Boston - DSM to BOS

Did You Know?

American Airlines has 490 connecting flights between Des Moines, IA and Boston.
You must make at least one connection to fly from Des Moines, IA to Boston.

Cheap Domestic Flights from Des Moines - DSM

Flights
Airline
Lowest Price
United, US, American
$225
US, United, Delta
$330
United, American, Delta, US
$321

Cheap Domestic Flights to Boston - BOS

Flights
Airline
Lowest Price
American, United, AirTran, Delta, US
$337
United, US, American, AirTran, Delta
$385
US, Delta, United, American
$240
United, US, Delta, American
$292
US, Delta, United
$420
American
$322
Delta, American
$292
American
$433
American, US, AirTran, United
$216
AirTran, United, Delta, US
$333
AirTran, American, United, US
$352
United, AirTran, US, Delta
$329
US, United, Delta
$373
US, Delta, United
$382
AirTran, United, Delta, US, American
$226
US, United, American, Alaska, Delta
$80
Delta, United, US, AirTran
$329
United, American, Delta, US, Alaska
$165
United, Delta, US
$334
US, United, Delta, AirTran, American
$255
US, Delta, United, American, AirTran
$230
US, Delta, United
$334
US, AirTran, Frontier, United, Delta, American
$254
American, Delta, US, United
$348
AirTran, United, Delta, US, Frontier, American
$209
Frontier, Delta, AirTran, United, US, American
$269
Cheap Flights from Des Moines to Boston, from $333 Round trip from DSM to BOS